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Pepsin

Yzym-PEP

-- Series of Pepsin

Yzym-PEP is a series of powder-type concentrated Pepsin enzyme extracted from porcine gastric mucosa through exclusive skill. Its zymogen (pepsinogen) is released by the chief cells in the stomach and that degrades food proteins into peptides. It belongs to a digestive protease, a member of the aspartate protease family. It is one of three principal protein-degrading enzymes in the digestive system. The other two being chymotrypsin and trypsin. The three enzymes were among the first to be isolated in crystalline form. During the process of digestion, these enzymes, each of which is specialized in severing links between particular types of amino acids, collaborate to break down dietary proteins into their components, i.e., peptides and amino acids, which can be readily absorbed by the intestinal lining. Pepsin is the most efficient in cleaving peptide bonds between hydrophobic and preferably aromatic amino acids such as phenylalanine, tryptophan, and tyrosine.
The product is manufactured fully under the standard of NF, BP, CP and GMP condition.
CAS No.: 9001-75-6
EINECS No.: 232-629-3
MF: C6H15O12P3
Grade: Pharmaceutical, Food, Feed and Industrial Grade.
HS: 35079090.

SPECIFICATIONS:
Appearance
:Powder
Color
:White, yellowish, or amorphous
Odor
:(meaty) not offensive smell
Source
:Porcine gastric mucosa
Purity
:99%
Pepsin potency
:Min.1:3,000NF/EP
Loss on drying
:5.0% max
Particle size
:80 mesh max
Solubility
:Soluble in water, insoluble in most organic solvents
Aerobic plate count
:10,000cfu/g max
Yeast and moulds
:100/g max
Escherichia coli
:Absent
Salmonella
:Absent

Customized Enzyme Activity:

1. for Pharmaceutical:
Commodity Name
Type
Activity (≥)
Grade
Yzym-PEP3M
Powder
3,000NFU/g
Pharmaceutical
Yzym-PEP10M
Powder
10,000NFU/g
Pharmaceutical
Yzym-PEP13M
Powder
13,000NFU/g
Pharmaceutical
Yzym-PEP15M
Powder
15,000NFU/g
Pharmaceutical
Yzym-PEP19M
Powder
19,000NFU/g
Pharmaceutical

2. for Food:
Commodity Name
Type
Activity (≥)
Grade
Yzym-PEP3FO
Powder
3,000NFU/g
Food
Yzym-PEP10FO
Powder
10,000NFU/g
Food
Yzym-PEP13FO
Powder
13,000NFU/g
Food
Yzym-PEP15FO
Powder
15,000NFU/g
Food
Yzym-PEP19FO
Powder
19,000NFU/g
Food

3. for Feed:
Commodity Name
Type
Activity (≥)
Grade
Yzym-PEP3FE
Powder
3,000NFU/g
Feed
Yzym-PEP10FE
Powder
10,000NFU/g
Feed
Yzym-PEP13FE
Powder
13,000NFU/g
Feed
Yzym-PEP15FE
Powder
15,000NFU/g
Feed
Yzym-PEP19FE
Powder
19,000NFU/g
Feed

4 for Leather:
Commodity Name
Type
Activity (≥)
Grade
Yzym-PEP3SK
Powder
3,000NFU/g
Leather
Yzym-PEP10SK
Powder
10,000NFU/g
Leather
Yzym-PEP13SK
Powder
13,000NFU/g
Leather
Yzym-PEP15SK
Powder
15,000NFU/g
Leather
Yzym-PEP19SK
Powder
19,000NFU/g
Leather

FUNCTION CONDITION:
--pH: Optimum at 1.6-1.8. Most favorable at pH 2.0. Inactive at pH 6.5 and above; It is narrower for crystalline pepsin than for a crude preparation;
--Temperature: Effective between 37 °C and 42 °C.

UNIT DEFINITION:
1 unit of Pepsin activity is contained in that amount of standard preparation, which upon incubation at 25.0 ± 0.1 °C for one minute with a suitable preparation of pure hemoglobin will cause the decomposition of the hemoglobin to such an extent that the amount of hydroxyaryl substances liberated will, upon reaction with Folin-Ciocalteus-Phenol-Reagent, result in the formation of a colored solution of equal intensity to that, resulting from the reaction of 1 micromole of tyrosine with the reagent.

APPLICATION FIELDS & EFFICACY:
--Used in medicine to cure chronic of atrophic gastritis, gastric cancer and malignant anemia;
--Used as the digestive for the dyspepsia caused by over taking protein foods and lack of stomach protease caused by digestive hypo function in the recovering period after illness;
--Used in food and beverages manufacturing to modify and provide whipping qualities to soy protein and gelatin to modify vegetable proteins for use in nondairy snack items, to make precooked cereals into instant hot cereals, and to prepare animal and vegetable protein hydrolysates for use in flavoring foods and beverages;
--Used as feed additive for animal digestive and illness cure;
--Used in the leather industry to remove hair and residual tissue from hides and in the recovery of silver from discarded photographic films by digesting the gelatin layer that holds the silver.

PACKAGING & DELIVERY:
25kgs/bag or drum. Or package as per requirement.

STORAGE:
Air-tight. Avoid sun light and keep at a temperature of 2°C to 8°C.

EXPIRATION:
Stable for 12 months when stored in original unopened package at 4°C- 8°C.

SAFETY:
Enzyme preparations belong to protein, which may induce sensitization and cause allergic type reactions in sensitized individuals. Prolonged contact may cause minor irritation for skin, eyes or mucous membrane of nose, so any direct contiguity with human body should be avoided. If irritation or allergic response for skin or eyes develops, consult a doctor.


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